comparison of analgesic effect between gabapentin and diclofenac on post-operative pain in patients undergoing tonsillectomy

نویسندگان

visnja nesek adam university department of anesthesiology, resuscitation and intensive care, university of osijek, osijek, croatia; university department of anesthesiology, resuscitation and intensive care, university of osijek, osijek, croatia. tel: +38-5913712136, fax: +385013712111

چکیده

background tonsillectomy is a common procedure causing considerable postoperative pain. postoperative pain intensity of 60 - 70 in the scale of visual analog scale (vas) has been reported up to 3 - 4 days which could continue until 11 days after the surgery. objectives the current study aimed to compare the analgesic effect of gabapentin and diclofenac on pain after tonsillectomy with the control group. patients and methods in this double-blind, placebo-controlled clinical trial, 90 patients aged 10-25 years, asa classes i and ii were randomly selected to receive 20 mg/kg oral gabapentin (n = 30), 1.0 mg / kg rectal diclofenac (n = 30) or placebo (n = 30) preoperatively. pain was evaluated postoperatively on a visual analogue scale at 2, 6, 12 and 24 h. opioid consumption in the first 24 h after surgery and the side effects were also recorded. results there was no significant difference in terms of age, sex, and time of surgery in the three groups. patients in the gabapentin and diclofenac groups had significantly lower pain scores at all-time intervals than those in the placebo group. the total meperidine consumed in the gabapentin (14.16 ± 6.97 p = 0.001) and diclofenac (16.66 ± 8.95, p = 0.004) groups was significantly less than that of the placebo (33.4 ± 13.97) group. the frequency of side effects such as vomiting, dizziness, and headache was not significantly different among the groups. conclusions it can be concluded that gabapentin and diclofenac reduced postoperative pain and opioid consumption without obvious side effects.

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منابع مشابه

Comparison of Analgesic Effect Between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy

BACKGROUND Tonsillectomy is a common procedure causing considerable postoperative pain. Postoperative pain intensity of 60 - 70 in the scale of visual analog scale (VAS) has been reported up to 3 - 4 days which could continue until 11 days after the surgery. OBJECTIVES The current study aimed to compare the analgesic effect of gabapentin and diclofenac on pain after tonsillectomy with the con...

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Comparison of Analgesic Effect between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy

Dear Editor, We have examined attentively the latest manuscript by Yeganeh Mogadam et al. entitled " Comparison of Analgesic Effect between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy " available in Archives of Trauma Research (1). Ninety patients were included to receive 20 mg/kg oral gabapentin (n = 30), 1.0 mg/kg rectal diclofenac (n = 30) or placebo...

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Comparison of Analgesic Effect between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy

Implication for health policy/practice/research/medical education: This is a brief comment on the very interesting comparative effectiveness study of gabapentin and diclofenac on pain after tonsillectomy. Copyright © 2013, Kashan University of Medical Sciences; License Kowsar Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://crea...

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Comparison of Analgesic Effect between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy – is the evidence enough?

I read with great interest the work published by Mogadam et al., entitled "Comparison of Analgesic Effect between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy" (1). I found the article quite interesting, however I have few questions that should be answered before we start to prescribe gabapentin or diclofenac to all patients before tonsillectomy, with th...

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Analgesic Effects of Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy

We studied the article by Yeganeh Mogadam et al. (1) with great interest, “comparison of analgesic effect between gabapentin and diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy”. The authors had demonstrated that administration of preoperative gabapentin and diclofenac significantly reduced postoperative pain, and the amount of opioid consumption. Although the article was...

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عنوان ژورنال:
archives of trauma research

جلد ۲، شماره ۲، صفحات ۹۹-۱۰۰

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